6th Infantry activated 16 October 1950 in Germany.
Reorganized 1 June 1958 as a parent regiment under the Combat Arms Regimental System.
Withdrawn 16 June 1989 from the Combat Arms Regimental System and reorganized under the United States Army Regimental System.
In October 1950 the 6th Infantry was reconstituted as a regular infantry regiment forming the U.S. garrison in West Berlin, designated as Berlin Command. The existing garrison units, the 16th Constabulary Squadron and the 3rd Battalion, 16th Infantry, were reflagged as the 1st and 3rd Battalions, 6th Infantry. The 2nd Battalion was assembled from troops in West Germany.
In 1958 Berlin Command was reorganized as a Pentomic unit. The 6th Regiment was reorganized as the 2nd and 3rd Battle Groups, 6th Infantry. The 1st Battalion (1st Battle Group) was changed to 1st Armored Rifle Battalion. On 1 December 1961 the occupation forces were designated Berlin Brigade. In 1964, Berlin Brigade was reorganized again. 2nd and 3rd Battle Groups were redesignated 2nd and 3rd Battalions, 6th Infantry, and 4th Battalion was also formed from cadre of the two battle groups.
On 17 May 1967, the 1st Battalion, 6th Infantry was reorganized as a standard Infantry Battalion and was assigned to the 198th Light Infantry Brigade, in the Americal (23rd Infantry) Division. The 1–6th Infantry was the division's first element ashore, arriving at Chu Lai in October to participate in its thirty-fifth campaign and ninth war. After a brief initial operation south of Duc Pho, the battalion was assigned the mission of securing the installation at Chu Lai.
1–6th Infantry participated in Task Force Oregon, Task Force Miracle, Operation Wheeler/Wallowa, Operation Burlington Trail, and had the mission of protecting Americal Division Headquarters and Chu Lai Defense Command from enemy ground mortar and rocket attacks. The 1st Battalion, 6th Infantry was awarded the Valorous Unit Citation for its victory at the battle of Lo Giang, 7–11 February 1968. Task Force Miracle was formed in February 1968 during the enemy's Tet offensive when the city of Da Nang was threatened by the 60th Main Force Viet Cong Battalion. The 1st Battalion, 6th Infantry and 2nd Battalion, 1st Infantry assisted the Marines in the fighting. After four days of fierce fighting, the threat to Da Nang was obliterated and the task force was deactivated and returned to the Americal area of operation. During the Vietnam War, the Sixth was awarded streamers – COUNTEROFFENSIVE PHASE III, TET COUNTEROFFENSIVE, COUNTEROFFENSIVE PHASE IV, COUNTEROFFENSIVE PHASE V, COUNTEROFFENSIVE PHASE VI, TET 69 / COUNTEROFFENSIVE, SUMMER-FALL 1969, WINTER-SPRING 1970, SANCTUARY COUNTEROFFENSIVE, COUNTEROFFENSIVE PHASE VII, and CONSOLIDATION I.
On 15 February 1969, the battalion was released from the 198th Light Infantry Brigade and assigned to the 23rd Infantry Division, Americal Division. On 13 September 1972 was reassigned to the 1st Armored Division, and was posted at Stork Barracks in Illesheim, West Germany.
In 1984, the regiment was split again, this time between Germany and the United States. The 1st Battalion was assigned to the 1st Brigade, 1st Armored Division in Illesheim, Germany. 2nd Battalion, 6th Infantry Regiment Coin of Excellence, 1984–1992, Erlangen, Germany. The 2nd Battalion was assigned to the 2nd Brigade, 1st Armored Division in Erlangen, Germany. The three Berlin Brigade battalions were reflagged as the 4th, 5th and 6th Battalions, 502nd Infantry. The 3rd and 4th Battalions were assigned to the 2nd Brigade, 5th Infantry Division at Fort Polk, Louisiana, where elements participated in Operation Just Cause in Panama in 1989, earning campaign streamer – PANAMA, and the Valorous Unit Award for Panama. In 1989, the unit also received the Army Superior Unit Award. The 5th Battalion was assigned to the 3rd Brigade of the 5th Infantry Division. The 6th Battalion and 7th Battalion were assigned to 3rd Brigade, 1st Armored Division, Bamberg, Germany. In 1990, the 6th and 7th Battalions were called on to participate in the regiment's tenth war, Operation Desert Shield / Desert Storm. During that war in the Persian Gulf, the regiment earned campaign streamers – DEFENSE OF SAUDI ARABIA, LIBERATION AND DEFENSE OF KUWAIT, and CEASE-FIRE, as well as Valorous Unit Citations for Iraq and Iraq-Kuwait.
In 1993, the 5th Infantry Division was deactivated, and the 3rd, 4th and 5th Battalions were re-flagged under the 2nd Armored Division at Fort Hood; the 1st Battalion moved from Illesheim to Vilseck, Germany, and came under the 3rd Brigade, 3rd Infantry Division; and the 6th and 7th Battalions were deactivated.